scientific evidence regarding the effects of moonlight on plantsyolink hub

Bardin A., Boulle N., Lazennec G., Vignon F., Pujol P. Loss of ERbeta expression as a common step in estrogen-dependent tumor progression. Moreover, the number of publications grouping women according to pre- or post-diagnosis intake criteria is small. This fact was not taken into account in previous meta-analyses, and thus it may justify the discrepancies amongst them. Santo A.S., Santo A.M., Browne R.W., Burton H., Leddy J.J., Horvath S.M., Horvath P.J. Dong J.Y., Qin L.Q. In like manner, a meta-analysis by Simental-Menda et al. Licensee MDPI, Basel, Switzerland. Create your free account or Sign in to continue. These positive effects were associated with 54 mg/day of genistein and 600 mg/day of synthetic isoflavone ipriflavone. Adlercreutz H., Markkanen H., Watanabe S. Plasma concentrations of phyto-oestrogens in Japanese men. The effect of the moon on planting times is stated as a matter of fact in such popular publications as The Old Farmer's Almanac and books such as Gardening and Planting by the Moon 2018, and, of course, calendars such as The Biodynamic Sowing and Planting Calendar 2018. The https:// ensures that you are connecting to the The gravitational attraction between the Earth and the Moon produces two bulges in the ocean on opposite sides of the Earth. With regard to the published meta-analysis, the studies included were restricted to randomized controlled trials. Despite the positive effect of isoflavones, the authors emphasized that the effects took a long time to appear. Another meta-analysis, conducted by Zhao et al. In the meta-analysis reported by Applegate et al. By contrast, it seems that soy isoflavones do not lead to a meaningful protective effect on cardiovascular risk. On the contrary, women who were already equol producers did not obtain any additional benefit from supplements of equol or isoflavones. Finally, it is important to mention that despite the fact that potential isoflavone adverse effects have been widely studied, little is known about the side effect of the bacterial metabolite equol. In some cases the purported effect may depend on external cues, such as the amount of moonlight. There are a total of 15 3 = 3375 possible outcomes. Moonlight sonata. Acid rain also removes minerals and nutrients from the soil that trees need to grow. Isoflavone excretion occurs mainly through urine and feces, primarily in the conjugate forms, and up to 95% takes place in 24 h [43]. Sex and long-term soy diets affect the metabolism and excretion of soy isoflavones in humans. Overall, evidence regarding the use of isoflavones in cancer prevention suggests that they may be useful in reducing the risk of suffering from some types of cancer, such as breast and endometrial cancer, two of the types for which the association between isoflavone intake and cancer risk has been studied more in-depth. Batterham T.J., Shutt D.A., Braden A.W.H., Tweeddale H.J. During menopause, there is a loss of bone density that can cause osteoporosis. However, there is still a great heterogeneity among studies, which makes the current data inconclusive. CVD: cardiovascular disease, LDL: low-density lipoprotein. As with other phenolic compounds, isoflavones can be presented as free forms (aglycones) or conjugated with carbohydrates (glycosides). In contrast, the effects on bone resorption biomarkers were more favorable in overweight or obese women than in women with a healthy weight. To address the link between lunar phases and agriculture from a scientic perspective, we conducted a review of textbooks and monographs used to teach agronomy, botany, horticulture and plant physiology; we also consider the physics that address the e ects of the Moon on our planet. The difference for isoflavones required to find an effect can be due to variations in the amount of isoflavone intake between both populations. In this sense, the authors suggested that the composition of the gut microflora may influence isoflavone absorption and metabolism and could affect the production of isoflavone metabolites, which, in turn, could mediate their biological activity. It is also important to mention that isoflavones could act as potential anticancer compounds due to their antioxidant role in malignant cell proliferation and differentiation (Figure 5). The dose of isoflavones ranged from 30 to 200 mg/day. Li L., Lv Y., Xu L., Zheng Q. Quantitative efficacy of soy isoflavones on menopausal hot flashes. Since hepatic lipase and lipoprotein lipase hydrolyze triglycerides into their constituents glycerol and fatty acids, their activation results in the delivery of the fatty acids to tissues such as muscle and adipose tissue. Zhao T.T., Jin F., Li J.G., Xu Y.Y., Dong H.T., Liu Q., Xing P., Zhu G.L., Xu H., Miao Z.F. Sarri G., Pedder H., Dias S., Guo Y., Lumsden M.A. Hosoda K., Furuta T., Yokokawa A., Ishii K. Identification and quantification of daidzein-7-glucuronide-4-sulfate, genistein-7-glucuronide-4-sulfate and genistein-4,7-diglucuronide as major metabolites in human plasma after administration of kinako. Furthermore, isoflavones are associated with proteins; thus, alcohol extraction and processing diminish isoflavone content in foodstuffs such as fermented soybean, tofu or soy beverages. van der Schouw Y.T., Kreijkamp-Kaspers S., Peeters P.H., Keinan-Boker L., Rimm E.B., Grobbee D.E. Due to a decline in sunlight, the development of leaves . The meta-analysis included 15 studies in which the number of participants ranged from 30 to 252. Prospective study on usual dietary phytoestrogen intake and cardiovascular disease risk in Western women. Hua et al. Chalvon-Demersay T., Azzout-Marniche D., Arfsten J., Egli L., Gaudichon C., Karagounis L.G., Tom D. A Systematic Review of the Effects of Plant Compared with Animal Protein Sources on Features of Metabolic Syndrome. However, some limitations were found in these prospective studies, such as the small sample size of the cohorts and the unspecific definition of high, moderate and low isoflavone intake. (2017) conducted a meta-analysis with ten observational studies to assess the association between the isoflavone compounds daidzein, genistein and equol, and breast cancer [61]. Regarding blood pressure, inconsistent results were reported in three further interventional studies (n = 406 healthy, postmenopausal or obese participants aged 5079 years) either in diastolic or systolic blood pressure, after a supplementation with soy-protein. Matulka R.A., Matsuura I., Uesugi T., Ueno T., Burdock G. Developmental and Reproductive Effects of SE5-OH: An Equol-Rich Soy-Based Ingredient. Effects of isoflavones in cardiovascular disease-related markers. Simental-Menda L.E., Gotto A.M., Atkin S.L., Banach M., Pirro M., Sahebkar A. In another systematic review of three observational studies (including 68,748 participants), low evidence of isoflavones was shown in the prevention of cardiovascular diseases [61]. 19% reduction in endometrial cancer risk. With regard to isoflavone content in foodstuffs, it has been observed that in soybeans, the amount of these phenolic compounds ranges from 1.2 to 4.2 mg per g on dry weight, whereas in red clover, the amount varies between 10 and 25 mg per g on dry weight [15,16]. The light of the moon also influences animals that are active in daytime. DOI: 10.1093/OXFORDJOURNALS.AOB.A087491 Corpus ID: 89019113; Effects of Moonlight on Flower Induction in Pharbitis nil, Using a Single Dark Period @article{KadmanZahavi1987EffectsOM, title={Effects of Moonlight on Flower Induction in Pharbitis nil, Using a Single Dark Period}, author={Avishag Kadman-Zahavi and Dovrat Peiper}, journal={Annals of Botany}, year={1987}, volume={60}, pages={621-623} } "It's not. ), 2CIBEROBN Physiopathology of Obesity and Nutrition, Institute of Health Carlos III, 01006 Vitoria, Spain, 3Bioaraba Health Research Institute, 01002 Vitoria, Spain. aimed to compare the effects of animal and plant-sourced proteins on lipemia and blood pressure [60]. Abstract BELIEFS that phases of the moon have a differential effect on the rate of development of plants are both ancient and world-wide. Isoflavones could be used as an alternative therapy for pathologies dependent on hormonal disorders such as breast and prostate cancer, cardiovascular diseases, as well as to minimize menopausal symptoms. Isoflavones have received attention due to their putative healthy properties. Moreover, an increase in thyroid hormone levels after isoflavone intake by food supplements has not been observed, and no side effects were confirmed with regard to the endometrial thickness or histopathological changes in the uterus. They observed that it was dose-dependent at low to moderate soybean consumption. The majority of the studies that used display stimuli, such as photos, 3D images, virtual reality, and videos of natural landscapes, confirmed that viewing natural scenery led to more relaxed body responses than viewing the control. The aim of the present review is to gather the scientific evidence existing nowadays on the main beneficial effects of isoflavones on health: bone health, cardiovascular risk, cancer and menopausal symptoms. Proof by rational experiment seems to have been. Two of the studies also revealed that women who were able to produce equol or who had received equol supplementation could have had a greater benefit from isoflavones [53]. (2018) showed no effect of soy isoflavones on plasma concentrations of lipoprotein a (Lpa), a low-density lipoprotein associated with increased cardiovascular risk due to its pro-thrombotic and atherogenic properties [63]. Soy products (0.05130 g/day) and total isoflavones (0.28 to 63 mg/day). The authors reported that neither soy food intake nor circulating isoflavones were associated with a reduced risk of prostate cancer. It has been described that after the oral intake of isoflavones, their peak plasma concentration in humans occurs at around seven hours [33]. In fact, in 2015, in relation to the possible adverse effects on the mammary gland, uterus and thyroid, the European Food Safety Agency (EFSA) offered a scientific opinion with regards to the assessment of potential increased risk in peri- and postmenopausal women who took food supplements that contained isolated isoflavones. In the systematic review reported by Perna et al. However, more studies are required to provide stronger evidence. In a more recent systematic review, including two meta-analyses, as well as one multicenter and randomized controlled trial, Chen and his team concluded that isoflavones reduced lumbar spine bone mineral density loss [53]. Regarding the mechanisms by which isoflavones act to alleviate vasomotor symptoms, is has been proposed that they bind to estrogen receptors and activate endothelial nitric oxide synthase (eNOS) transcription, leading to eNOS synthesis and nitric oxide production, the main mediator of vasodilatation, which allows cutaneous heat dissipation [91] (Figure 6). (2016) conducted a meta-analysis of 18 studies involving 16,917 colorectal cancer cases in 559,486 participants [78]. Even though red clover has a greater amount of isoflavones, it is not an edible plant, and it is consumed as a food complement. Soy isoflavones osteoprotective role in postmenopausal women: Mechanism of action. Science is Knowledge Space & Physics The Effects of Moonlight May 22, 1858 Professor Piazza Smyth, the Astronomer Royal for Scotland, in his interesting account of a recent scientific. Micek A., Godos J., Brzostek T., Gniadek A., Favari C., Mena P., Libra M., Del Rio D., Galvano F., Grosso G. Dietary phytoestrogens and biomarkers of their intake in relation to cancer survival and recurrence: A comprehensive systematic review with meta-analysis. Kurzer M.S., Xu X. Dietary phytoestrogens. Efficacy of phytoestrogens for menopausal symptoms: A meta-analysis and systematic review. Effects of isoflavones in different cancer types. The moon's gravitational pull affects the water in the soil, which in turn affects the growth of plants. and transmitted securely. (2017) also analyzed eight studies of prostate cancer, and they found an association between isoflavone intake and prostate cancer risk [61]. As in the previous study, the onset of soy isoflavones was very slow in comparison with other non-hormonal treatments. Chen M.N., Lin C.C., Liu C.F. A systematic review and meta-analysis of the effects of isoflavone formulations against estrogen-deficient bone resorption in peri- and postmenopausal women. (2016), nine studies addressed to menopausal women and focused on bone health were analyzed [52]. Nevertheless, the results do not seem entirely conclusive, as there are discrepancies among the studies included in the systematic reviews and in the meta-analyses, probably related to their experimental designs. Daidzein is first converted into dihydrodaidzein, which is the precursor of both equol and O-demethylangolensin (O-DMA) [37]. Although the mechanisms of action of isoflavones are not completely understood, it seems that isoflavones not only reduce the rate of bone resorption but also increase the rate of bone formation. Hormone replacement therapy has been proven to be effective in reducing vasomotor symptoms, although isoflavones have gained popularity as an alternative treatment to hormone replacement therapy to relieve menopausal symptoms. 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